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The London Allergy and Immunology Centre (LAIC) is one of the UK’s most established and comprehensive private allergy services, bringing together expert GMC-registered consultants in allergy and clinical immunology, paediatric allergy, dermatology, and ENT under one roof. We provide accurate diagnosis and effective, evidence-based treatment for adults, children, and families experiencing allergic and immunological conditions.
Our diagnostic approach is grounded in the most current international guidelines, including the EAACI 2025 guidelines on IgE-mediated food allergy and the EMA allergen immunotherapy guideline (January 2026), which sets new standards for allergen product development and specialist oversight. We use clinically validated tests and avoid unproven or pseudoscientific allergy tests, which are prevalent in the unregulated private sector.
Affiliated & Accredited
BSACI
AAAAI
GMC Registered
Global Allergy Network of Excellence
Why Choose the London Allergy & Immunology Centre?
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Consultant-Led Every Time
Every consultation is conducted personally by a GMC-registered specialist consultant — never a nurse or GP alone. Our Medical Director, Professor Michael Rudenko MD PhD FAAAAI, has decades of research experience in allergy, asthma, immunotherapy, and clinical trials.
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Advanced Molecular Diagnostics
We offer ALEX³ component-resolved diagnostics (300 allergens and molecular components in a single blood test), ISAC molecular profiling, and a full range of skin prick, intradermal, patch, and challenge tests — enabling precision diagnosis beyond standard IgE screening.
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Disease-Modifying Treatments
We are one of very few UK private clinics offering the full range of allergen immunotherapy: subcutaneous immunotherapy (SCIT), sublingual immunotherapy (SLIT), venom immunotherapy (VIT), peanut oral immunotherapy (Palforzia®), and biologic therapies including omalizumab (Xolair).
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Evidence-Based, Not Pseudoscientific
We use only validated, scientifically proven tests and treatments. We do not offer unproven tests such as hair analysis, kinesiology, Vega testing, or non-specific food intolerance panels that are not supported by EAACI or BSACI evidence-based guidelines.
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Global Network & Continuity of Care
As part of the Global Allergy Network of Excellence, we welcome patients transferring immunotherapy from the US, Europe, Australia, New Zealand, and beyond. We provide long-term care, annual reviews, specialist second opinions, and transition from paediatric to adult allergy services.
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Fast Access & Flexible Appointments
Consultant appointments are typically available within one week, and same-day urgent video consultations can often be arranged. No GP referral is required for self-pay patients. We also offer secure UK telemedicine appointments for remote consultations and selected postal testing pathways.
Conditions We Diagnose and Treat
Our consultants manage the full spectrum of allergic and immunological conditions. This is not an exhaustive list — if your condition is not listed below, please contact us to discuss your symptoms.
Food Allergy
- Peanut allergy (including Palforzia® OIT)
- Tree nut, milk, egg, wheat, soya allergy
- Fish and shellfish allergy
- Sesame and mustard allergy
- Oral allergy syndrome (pollen-food)
- Multiple food allergies
Airborne & Environmental
- Allergic rhinitis (hay fever)
- Perennial rhinitis (dust mite, mould, pet)
- Allergic asthma
- Cat, dog, horse allergy
- House dust mite allergy
- Mould and fungal allergy
Skin & Systemic
- Anaphylaxis investigation and management
- Chronic urticaria (hives)
- Angioedema
- Atopic eczema / dermatitis
- Allergic contact dermatitis
- Mastocytosis / elevated tryptase
Drug & Venom Allergy
- Penicillin and antibiotic allergy investigation
- NSAID / aspirin hypersensitivity
- Anaesthetic and perioperative allergy
- Vaccine allergy assessment
- Wasp and bee venom allergy (VIT)
- Drug challenge and de-labelling
ENT & Respiratory
- Rhinosinusitis and nasal polyps
- Eustachian tube dysfunction
- Non-allergic rhinitis
- Vocal cord dysfunction
- Difficult asthma assessment
- Anti-IgE biologic therapy
Immunology
- Recurrent infections (primary immunodeficiency)
- Hypogammaglobulinaemia
- Autoimmune conditions
- CMV and EBV-related immunological issues
- Immunodeficiency screening
- Complex immune dysregulation
Allergy Testing — What We Offer
We offer more than 600 allergy tests across all clinically validated methods. Per the EAACI 2025 guidelines, component-resolved diagnostics (CRD) should now be used as standard to distinguish primary sensitisation from cross-reactive responses and to guide immunotherapy selection. Our full diagnostic pathway reflects this.
ALEX³ Molecular Allergy Test
300 allergens and molecular components tested from a single blood sample. Identifies specific sensitising proteins (e.g. Ara h 2 for peanut, Bet v 1 for birch pollen), enabling precise risk stratification and the distinction between genuine allergy and harmless cross-reactivity.
ISAC Component-Resolved Diagnostics
Multiplex IgE testing on a biochip platform. Particularly useful for patients with complex multi-allergen sensitivities, polysensitised individuals, and cases where cross-reactive carbohydrate determinants (CCDs) may confound standard IgE results.
Skin Prick Testing (SPT)
Fast, safe, and highly sensitive. Results available within 20 minutes. Safe from birth when clinically appropriate. Used for inhalant allergens, foods, drugs, insect venoms, and latex. Performed by trained specialist nurses or directly by the consultant.
Specific IgE (RAST) Blood Tests
Quantitative measurement of allergen-specific IgE for over 600 individual allergens. Particularly useful when skin testing is not possible (e.g. severe eczema, antihistamine use, dermographism). Results inform risk level and immunotherapy candidacy.
Allergen Challenge (Provocation) Tests
Supervised oral food challenges (OFC) and drug provocation tests — the gold standard for confirming or excluding allergy. Conducted in clinic with full resuscitation facilities and medical supervision. Used for diagnosis, threshold assessment, and de-labelling.
Patch Testing & Other Specialist Tests
Patch testing for allergic contact dermatitis; urticaria histamine release testing; basophil activation testing; baseline serum tryptase; gluten and lactose intolerance investigations; intradermal testing for drug and venom allergy.
Important: We do not offer unvalidated tests including hair mineral analysis, applied kinesiology, Vega testing, Alcat tests, or broad IgG food intolerance panels not supported by evidence-based allergy guidelines. These tests are not recommended by EAACI, BSACI, or NICE and can lead to unnecessary dietary restriction.
Treatment Options
We offer the full spectrum of evidence-based allergy treatments, from emergency medication planning through to disease-modifying immunotherapy programmes. Every treatment plan is personalised by your consultant following a comprehensive diagnostic assessment.
Allergen Immunotherapy (AIT)
The only treatment that addresses the underlying cause of allergy, not just symptoms. Suitable for hay fever, allergic asthma, cat and dog allergy, house dust mite allergy, and venom allergy. Available as:
- SCIT — subcutaneous injections (conventional, cluster, rush, ultra-rush)
- SLIT — sublingual drops or tablets (home-based, 3–5 years)
- VIT — venom immunotherapy for wasp and bee sting allergy
Peanut Oral Immunotherapy (Palforzia®)
Recommended by EAACI 2025 guidelines for children and adolescents aged 4–17 with confirmed peanut allergy. The only licensed medicinal OIT product in the UK. BSACI 2024 prescribing guidance followed. Full pre-treatment food challenge workup required.
Biologic Therapies
Omalizumab (Xolair) — anti-IgE monoclonal antibody for allergic asthma, chronic urticaria, and as an adjunct to OIT in highly sensitised patients. Suitability assessed individually based on age, diagnosis, IgE level, and risk profile. EAACI 2025 also supports omalizumab for IgE-mediated food allergy.
Emergency Medication & Action Plans
Personalised written emergency action plans, adrenaline auto-injector (EpiPen, Jext) prescription and training, and assessment for EURneffy® (the MHRA-approved needle-free adrenaline nasal spray, available on private prescription from October 2025). School and workplace allergy plans provided.
Medication Review & Optimisation
Review and optimisation of antihistamines, nasal corticosteroids, bronchodilators, and leukotriene antagonists. Assessment for beta-blocker or ACE inhibitor drug interactions in venom allergy patients. Drug allergy de-labelling where appropriate.
Dietary Advice & Intolerance Testing
Clinically validated assessment for food intolerance including gluten sensitivity / coeliac disease and lactose intolerance. Practical dietary advice provided, with referral to an accredited dietitian where appropriate.
Who We See
Adults
Adults with newly developed or longstanding allergic conditions; those seeking a second opinion; patients wishing to explore immunotherapy or biologics; professionals requiring rapid diagnosis; expats and international patients relocating to London.
Children & Babies
Specialist paediatric allergy consultants for children of all ages, including babies. Food allergy investigation from weaning age; school allergy plans; assessment for peanut OIT; transition planning from paediatric to adult services at age 16–18.
Families
Families managing multiple allergies across generations; parents seeking reassurance and clarity; joint consultations for parent and child; comprehensive family allergy management plans; annual review packages.
Transferring Immunotherapy Patients
We welcome patients who have started allergen immunotherapy (allergy shots, SLIT, or OIT) abroad — in the US, Europe, Australia, or elsewhere — and are relocating to the UK. Subject to vaccine availability and contact with your originating physician.
Our London Clinic Locations
Harley Street
London W1
Our flagship clinic in the heart of London’s medical quarter. Comprehensive allergy, immunology, dermatology, ENT, and paediatric allergy services. Consultant appointments typically available within one week.
City of London
London EC
Convenient for professionals and City workers. Adult allergy and immunology consultations, allergy testing, and emergency plan reviews. Easy access by tube and rail.
East London
London E
Serving patients in East London and beyond. Allergy consultations, skin prick testing, and paediatric allergy services for families in the east of the city.
UK Telemedicine
Nationwide
Secure video consultations available across England, Scotland, Wales, and Northern Ireland. Ideal for follow-up appointments, results review, emergency plan discussions, and initial consultations where local testing can be arranged. Selected postal testing pathways available.
Your First Appointment — What to Expect
No GP referral is required for self-pay patients. Here is what a typical first allergy consultation involves:
Register & Book
Register online as a new patient at allergycentrelondon.co.uk, then book your consultation. Same-day urgent video appointments can often be arranged — call 020 3143 3449.
Detailed Clinical History
Your consultant will take a thorough history of your symptoms, previous reactions, co-existing conditions, family history, medications, and lifestyle factors. This takes as long as it needs to — no rushed appointments.
Allergy Tests (if appropriate)
Skin prick testing can be performed at the same visit when clinically appropriate (results within 20 minutes). Blood tests for specific IgE and molecular profiling (ALEX³, ISAC) are arranged and results reviewed at a follow-up appointment.
Diagnosis & Personalised Plan
Your consultant will explain your diagnosis clearly, provide a written summary, and agree a personalised treatment plan covering avoidance, medications, emergency planning, immunotherapy options, and any further investigations required. A detailed clinic letter is sent to you and, with consent, to your GP.
Insurance & Payment
We accept most major private health insurance plans. Self-pay patients are also welcome — no GP referral required. Contact us to confirm insurance acceptance before booking. For insured patients, a GP referral letter is often required by your insurer prior to the appointment.
Ready to Book Your Allergy Assessment?
Consultant appointments typically available within one week. Same-day urgent video consultations often possible.
Allergy/Immunology: 020 314 33449 | Paediatrics: 020 314 33446 | Dermatology: 020 314 33447 | ENT: 020 314 33448
Frequently Asked Questions
Important Notice
This page provides general information about our services and is not a substitute for personalised medical advice. All diagnostic and treatment decisions are made individually by a qualified consultant following a full assessment. In a medical emergency, call 999 immediately.
References
- Santos AF, Riggioni C, Agache I, et al. EAACI Guidelines on the Management of IgE-mediated Food Allergy. Allergy. 2025;80(1):1–28. doi:10.1111/all.16345
- European Medicines Agency. Guideline on Allergen Products: Production and Quality Issues. EMA/16166/2026. January 2026.
- BSACI. Guidance for Prescribing Palforzia® Peanut Oral Immunotherapy. British Society for Allergy and Clinical Immunology, 2024.
- Medicines and Healthcare products Regulatory Agency (MHRA). Approval of EURneffy® (adrenaline nasal spray 2 mg) for emergency treatment of anaphylaxis. July 2025.
- Sturm GJ, Varga EM, Roberts G, et al. EAACI Guidelines on Allergen Immunotherapy: Hymenoptera Venom Allergy. Allergy. 2018;73(4):744–764.
- Resuscitation Council UK. Emergency Treatment of Anaphylaxis: Guidelines for Healthcare Providers. May 2021.
- Chowdhury EA, Jadeja OC. The safety and efficacy of oral vs epicutaneous immunotherapy in peanut desensitisation. Front Allergy. 2025;6:1613237.
- National Institute for Health and Care Excellence (NICE). Anaphylaxis: Assessment and Referral after Emergency Treatment. CG134. 2011 (reviewed 2020).
- Anaphylaxis UK. EURneffy (Neffy) nasal adrenaline spray approved by MHRA. July 2025. anaphylaxis.org.uk
Page reviewed: June 2026 | London Allergy and Immunology Centre | privateallergy.uk




